CY-QUANT ELISA sCD146

Retour à la liste

default
Référence
7501
Statut
RUO
Sample
Sérum, plasma citrate ou EDTA
Quantité
96 tests
Detection
Colorimetrique
fiche specification
Colorimetrique
gamme mesure
100 à 1600 ng/ml
Application
Kits ELISA
Composition

- 3 x 2 barrettes de Réactif 1 (Barrette coatée)
- 3 flacons de Réactif 2 (Calibrant)
- 1 flacon de Réactif 3 (Solution de lavage)
- 1 flacon de Réactif 4 (Tampon de dilution)
- 1 flacon de Réactif 5 (Anti CD146-peroxydase)
- 1 flacon de Réactif 6 (TMB)
- 1 flacon de Réactif 7 (Plasma contrôle)
- 1 flacon de Réactif 8 (Solution stop)
- 1 support de barrettes

Un support plastique recouvert de fragments F(ab’)2 d’anticorps monoclonal anti CD146 humain (Réactif 1) fixe le sCD146 à doser. Le sCD146 est révélé à l’aide d’un second anticorps marqué à la peroxydase (Réactif 5) qui se fixe sur un déterminant antigénique différent et éloigné du premier. Le taux de peroxydase liée est mesuré par son activité sur le substrat TMB (Réactif 6). L’intensité du signal, après arrêt de la réaction (Réactif 8), est proportionnelle à la concentration de sCD146 présente initialement dans le milieu.
Date Nom du document Téléchargement
01/04/2015 Package insert CY-QUANT ELISA sCD146 EN (80.30 KB)
FR (82.42 KB)
Auteur Titre Année d'édition Revue
Bardin N et al.
Soluble CD146, a novel endothelial marker, is increased in physiopathological settings linked to endothelial junctional alteration
2003
Thromb Haemost
Malyszko J. et al.
Adiponectin is related to CD146, a novel marker of endothelial cell activation/injury in chronic renal failure and peritoneally dialyzed patients
2003
JCEM
Malyszko J. et al.
Is there a link between CD146, a novel adhesion molecule and other markers of endothelial dysfunction in nephrotic syndrome and continuous ambulatory peritoneal dialysis?
2005
Thromb Res
Pasquier E et al.
The first assessment of soluble CD146 in women with unexplained pregnancy loss. A new insight?
2005
Thromb Haemost.
Figarella-Branger et al.
Platelet-endothelial cell adhesion molecule-1 and CD146: soluble levels and in situ expression of cellular adhesion molecules implicated in the cohesion of endothelial cells in idiopathic inflammatory myopathies
2006
J Rheumatol.
Wrobel T et al.
sVE-cadherin and sCD146 serum levels in patients with multiple myeloma
2006
Clin.Lab.Haem.
Bardin N et al.
Increased Expression of CD146, a New Marker of the Endothelial Junction in
Active Inflammatory Bowel Diseas
2006
Inflamm Bowel Dis.
Malyszko J. et al.
Adipokines, Linking Adipocytes and Vascular Function in Hemodialyzed Patients, May Also Be Possibly Related
to CD146, a Novel Adhesion Molecule
2007
Clin Appl Thromb Hemost.
Klakamp SL et al.
Application of Analytical Detection Concepts to Immunogenicity Testing
2007
Anal. Chem.
Reumaux D et al.
Restoration of soluble CD146 in patients with Crohn's disease treated with the TNF- antagonist infliximab (p NA)
2007
Inflamm Bowel Dis.
Bardin N et al.
CD146 and its Soluble Form Regulate Monocyte Transendothelial Migration
2009
Arterioscler Thromb Vasc Biol
Kaspi E et al.
Soluble CD146 and APS: a potential biomarker of obstetrical complications?
2012
Lupus
Dogansen S.C. et al
The relationship between early atherosclerosis and endothelial dysfunction in type 1 diabetic patients as evidenced by measurement of carotid
2013
Cardiovascular Diabetology
Ilie M et al
Clinical value of circulating endothelial cells and of soluble CD146 levels in patients undergoing surgery for non-small cell lung cancer
2014
Br J Cancer
Gayat et al
Soluble CD146, a new endothelial biomarker of acutely decompensated heart failure
2015
Int J Cardiol
Kubena P et al
Plasma Levels of Soluble CD146 Reflect the Severity of Pulmonary Congestion Better Than Brain Natriuretic Peptide in Acute Coronary Syndrome
2016
Ann Lab Med
Nollet M. et al
A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule
2017
Oncotarget
Von Moos S. et al.
Vascular endothelial growth factor D is a biomarker of fluid overload in haemodialysis patients
2020
Nephrol Dial Transplant.